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Collagen doesn’t have to come in a bottle. Your body actually knows how to make it—it just needs a little encouragement. That’s where PDGF comes in.
PDGF, short for platelet-derived growth factor, is a regenerative treatment that taps into your body’s own natural repair system to restore youthful skin tone and texture. It's one of the powerhouse proteins released during PRP (platelet-rich plasma) treatments, playing a key role in healing, collagen synthesis, and cellular turnover.
PDGF (Platelet-Derived Growth Factor) is a protein found in your blood platelets that stimulates cell growth and tissue repair. When used in aesthetic treatments, it helps signal your body to produce new collagen and elastin, which can improve the appearance and texture of your skin.
It’s often delivered through platelet-rich plasma (PRP) procedures, where a small sample of your blood is processed to concentrate growth factors—such as PDGF—and then applied to or injected into targeted areas. The result is firmer, smoother, more radiant skin, using your own biology as the active ingredient.
PDGF-based treatments can help improve:
Because PDGF helps stimulate your body’s own tissue regeneration, it’s a versatile option that supports healing from the inside out.

The biggest benefit of PDGF is that it works with your body—not against it. Unlike synthetic injectables, PDGF is naturally derived from your own blood. That means fewer risks and a more holistic, regenerative approach to aesthetic care.
Other benefits include:
Results won’t happen overnight, but many clients start to notice smoother, brighter skin within a few weeks of their first session.

Most healthy adults are great candidates for PDGF-based treatments, especially if you’re looking for a gentle, natural option for improving skin tone, texture, or hair growth.
PDGF treatments are not recommended for anyone with bleeding disorders, active infections in the treatment area, or certain autoimmune conditions. If you're pregnant or nursing, it's best to wait.
Not sure if it’s right for you? Come in for a consultation—our team will guide you through your options and help you determine which one best suits your skin goals.
Recovery is minimal for most PDGF treatments. You may experience some redness, swelling, or sensitivity in the treated area (especially when paired with microneedling), but this usually subsides within 24–48 hours.
We’ll provide you with personalized aftercare instructions, but in general, avoid direct sun, skip makeup for the first day, and stick to gentle skincare. And definitely skip the gym for at least 24 hours—your skin will thank you.

Your results will develop gradually as the PDGF stimulates collagen and regenerates healthy tissue. Most clients begin to notice improvement in their skin tone and texture within 3–4 weeks, with peak results typically occurring around 6–12 weeks.
Because the results come from your body’s own healing process, they look natural and tend to last several months. For optimal results, we often recommend a series of treatments spaced several weeks apart.

At The Skin Agency, we don’t believe you should have to choose between results and relaxation. Our approach to regenerative treatments, such as PDGF, is high-tech and high-vibe.
Experienced, registered nurses will treat you in a beautiful, comfortable space designed to make you feel welcome and well cared for. We offer transparent pricing, online packages, and five convenient LA-area locations—because glowing skin should be easy.
Not exactly. PDGF is one of the key growth factors found in PRP; however, PRP contains the full concentration of platelets and plasma. PDGF is what helps signal your body to build new tissue—it’s one of the "active ingredients" in PRP.
Most people benefit from a series of 3–4 sessions spaced about 4–6 weeks apart. Your nurse will help create a personalized plan during your consultation, tailored to your specific goals.
Yes! Microneedling helps deliver the growth factors deeper into the skin and can boost results. It’s a very popular combo for treating texture, scars, and tone.
Yes. Since PDGF is derived from your own blood, it’s considered very safe with minimal risk of allergic reaction or rejection.
Most people report only mild discomfort during the procedure. We use numbing cream as needed to keep you comfortable.
Most PDGF treatments take about 45–60 minutes from start to finish.
We recommend waiting at least 24 hours before applying makeup to allow your skin time to heal and absorb the growth factors.
Usually, no. You may experience some redness or sensitivity, but you can typically resume your day right after treatment.
PDGF stimulates your body to produce its own collagen gradually, while fillers provide immediate volume using synthetic substances. They can work well together, depending on your goals.
Yes. PDGF-based treatments are available at all five of our LA-area locations. Just ask when booking and we’ll match you with the best treatment option for your goals.